Dan L. Nicolae

Publications

1. Effect of Subcutaneous Recombinant Human EPO in Cancer Patients Receiving Radiotherapy. British Journal of Cancer 77(11) , (1998),1996-2002 (Sweeney P, Nicolae DL, Vijayakumar S et al.).
   

2. Identification of Novel Susceptibility Loci for Inflammatory Bowel Disease. Proceedings National Academy of Science 95(13) ,(1998),7502-7507 (Cho JH, Nicolae DL et al.).
   

3. Loci on Chromosomes 2 (NIDDM1) and 15 Interact to Increase Susceptibility to Type 2 Diabetes in Mexican Americans. Nature Genetics 21, (1999),213-215 (Cox N, Frigge M, Nicolae DL, Concannon P, Hanis CL, Bell GI, and Kong A).
   

4. Discussion to ``Multipoint Linkage Analysis Using Affected Relative Pairs and Partially Informative Markers'' by Siegmund D and Teng J. Biometrics 54, (1999),1271-1274 (Nicolae DL, Frigge ML, Cox NJ and Kong A).
   

5. A Genome-Wide Scan Reveals a Maternal Susceptibility Locus for Pre-eclampsia on Chromosome 2p13. Human Molecular Genetics 8, (1999),1799-1805 (Arngrimsson R et al.).
   

6. Linkage and Linkage Disequilibrium in Chromosome 1 Band 1p36 in American Chaldeans with Inflammatory Bowel Disease. Human Molecular Genetics 9, (2000),1425-1432 (Cho JH, Nicolae DL et al.).
   

7. On a Randomization Procedure. American Journal of Human Genetics 67, (2000),1352-1355 (Kong A and Nicolae DL).
   

8. A Frameshift Mutation in NOD2 Associated with Susceptibility to Crohn's Disease. Nature 411, (2001), 603-606 (Ogura et al.).

9. MERLIN...and the Geneticist's Stone? Nature Genetics 30, (2002), 3-4 (Nicolae DL and Cox NJ).

10. A genome-wide scan for preeclampsia in the Netherlands Eur J Hum Gentics 9, (2001), 758-764. (Lachmeijer et al).

11. Effects of sequence and structure on the hypermutability of immunoglobulin genes Immunity 16, (2002), 123-134. (Michael et al).

12. A Theory of Statistical Models for Monte Carlo Integration JRSS 65, (2003), 585-618 ( Kong A, McCullagh P, Meng XL, Nicolae D and Tan Z).

13. Rapid Divergence in Expression between Duplicate Genes Inferred from Microarray Gene Expression Data Trends in Genetics 18, (2002), 609-613 (Gu Z, Nicolae D, Lu H, Li W-H).

14. Crohn's disease-associated NOD2 variants share a signaling defect in response to lipopolysaccharide and peptidoglycan Gastroenterology 124, (2003), 140-146 (Bonen et al).

15. Evidence for gene-environment interactions in a linkage study of asthma and smoking exposure J Allergy Clin Immunol 111, (2003), 840-846 (Colilla S et al).

16. Microarray analysis of changes in bone cell gene expression early after cadmium gavage in mice Toxicology and Applied Pharmacology 191, (2003), 272-293 (Regunathan A et al).

17. MDR1 Ala893 Polymorphism Is Associated with Inflammatory Bowel Disease Am J Human Genetics 73 , (2003), 1282-1292 (Brant SR et al).

18. Association studies for asthma and atopic diseases: a comprehensive review of the literature Respiratory Research 4 , (2004), 14 (Hoffjan S, Nicolae D, Ober C).

19. Effects of dog ownership and genotype on immune development and atopy in infancy J Allergy Clin Immunol 113, (2004), 307-314 (Gern et al).

20. Genetic variation in immunoregulatory pathways and atopic phenotypes in infancy J Allergy Clin Immunol 113, (2004), 511-518 (Hoffjan et al).

21. A genome scan in 260 inflammatory bowel disease-affected relative pairs Inflammatory Bowel Disease 10(1), (2004), 15-22 (Barmada et al).

22. Measuring the Relative Information in Allele-Sharing Linkage Studies Biometrics 60, (2004), 368-375 (Nicolae D, Kong A).

23. Regulation of IL-8 and IL-1beta expression in Crohn's disease associated NOD2/CARD15 mutations Human Molecular Genetics13(16) , 1715-1725 (Li et al).

24. Fine Mapping and Positional Candidate Studies Identify HLA-G as an Asthma Susceptibility Gene on Chromosome 6p21 American Journal of Human Genetics 76(2) , 349-357 (Nicolae et al).

25. Gene-environment interaction effects on the development of immune responses in the 1st year of life American Journal of Human Genetics76(4) , 696-704 (Hoffjan et al).

26. Information content in gene mapping Encyclopedia of Genomics, Proteomics and Bioinformatics , John Wiley & Sons (Nicolae DL).

27. The very 5' end and the constant region of Ig genes are spared from somatic mutation because AID does not access these regions The Journal of Experimental Medicine 202(100) , 1443-1454 (Longerich et al).

28. Dominant-Negative TLR5 Polymorphism Reduces Adaptive Immune Response to Flagellin and negatively associates with Crohn's Disease Am J Physiol Gastrointest Liver Physiol 290(6) , 1157-1163 (Gewirtz et al).

29. Phenotype-stratified genetic linkage study demonstrates that IBD2 is an extensive ulcerative colitis locus The American Journal of Gastroenterology 101 , 572-580 (Achkar et al).

30. Coverage and characteristics of the Affymetrix GeneChip Human Mapping 100K SNP set PLoS Genetics 2(5), e67 (Nicolae et al).

31. GEL: a novel genotype calling algorithm using empirical likelihood Bioinformatics 22(16) , 1942-1947 (Nicolae et al).

32. Quantifying the Amount of Missing Information in Genetic Association Studies Genetic Epidemiology 30(8) , 703-717 (Nicolae DL).

33. Testing untyped alleles (TUNA) - applications to genome-wide association studies > Genetic Epidemiology 30(8) , 718-727 (Nicolae DL).

34. Somatic hypermutation and class switch recombination in msh6-/-ung-/- double-knockout mice The Journal of Immunology 177(8) , 5386--5392 (Shen et al).

35. A Genome-Wide Association Study Identifies IL23R as an Inflammatory Bowel Disease Gene Science 314 (5804) , 1461 - 1463 (Duerr et al).