Case Control tests for samples with related individuals documentation
version 1.3 March 11, 2006
Copyright(C) Catherine Bourgain,
Carole Ober, Mary Sara McPeek
The following files describe the usage, input and output of our
software for Case Control tests for Samples with Related Individuals. This
program computes the Case-Control Quasi-Likelihood Score test (CC-QLS test)
and the Corrected Case-Control Chi2 test (corr-chi2) developped by
Bourgain, Hoffjan, Nicolae, Newman, Steiner, Walker, Reynolds, Ober and McPeek
(2003) in Novel
Case-Control Test in a Founder Population Identifies P-selectin as an Atopy
Susceptibility Locus, American Journal of Human Genetics 73:612-626
These two tests are suitable for case control analysis in any sample with
related individuals, including complex pedigrees, provided that their relationship
is known. We also provide with a program to compute kinship coefficients
and inbreeding coefficients in any general pedigree (the KinInbcoef program),
as these coefficients are required in the computation of the CC-QLS test and
the corr-chi2 test.
README
Changelog
Overview
Input
Output
Tips
Download the software