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Course Announcements

Last revised: 8/28/08

AUTUMN 2008


College Courses

STATISTICS 20000.  Elementary Statistics.
Sec 01: Keith Worsley, MWF 9:30-10:20 AM, Eckhart 133.
Sec 02: Phillip Lynch, MWF 12:30-1:20 PM, Eckhart 133.
PQ: Math 10600 or equivalent.
Required reading: Freedman, D., Pisani, R., and Purves, R. Statistics, 4th edition, 2007, Norton. ISBN-10: 0393929728, ISBN-13: 978-0393929720.

This course meets one of the general education requirements in the mathematical sciences. STAT 20000 may not be used in the statistics major. It is recommended for students who do not plan to take advanced statistics courses. Not open to students with credit for STAT 22000 or 23400.

This course introduces statistical concepts and methods for the collection, presentation, analysis, and interpretation of data. Elements of sampling, simple techniques for analysis of means, proportions, and linear association are used to illustrate both effective and fallacious uses of statistics.

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STATISTICS 22000=HDCP 22050.  Stat Meth And Applications.
Sec 01: Han Xiao, MWF 10:30-11:20 AM, Eckhart 133.
Sec 02: Xiaoquan Wen, MWF 1:30-2:20 PM, Eckhart 133.
PQ: 2 QTRS Calculus.
Required reading: Introduction to the Practice of Statistics, 6th edition by Moore, McCabe and Craig 2009, W. H. Freeman. ISBN-10: 1429216220 ISBN-13: 978-1429216227

Students who matriculate in the College after September 2008 may count either STAT 22000 or STAT 23400, but not both, toward the forty-two credits required for graduation.

This course introduces statistical techniques and methods of data analysis, including the use of computers. Examples are drawn from the biological, physical, and social sciences. Students are required to apply the techniques discussed to data drawn from actual research. Topics include data description, graphical techniques, exploratory data analyses, random variation and sampling, one- and two-sample problems, the analysis of variance, linear regression, and analysis of discrete data.

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STATISTICS 22400=HSTD 32400. Applied Regression Analysis
Sec 01:  Vanja Dukic, TTh 10:30-11:50 AM, Eckhart 133
PQ: HSTD 32700 or STAT 22000 or STAT 23400 or STAT 24400 or consent of instructor.
Required reading: Regression Analysis by Example 4th edition by Samprit Chatterjee, Ali S. Hadi

This course is an introduction to the methods and applications of fitting and interpreting multiple regression models. The main emphasis is on the method of least squares. Topics include the examination of residuals, the transformation of data, strategies and criteria for the selection of a regression equation, the use of dummy variables, and tests of fit. The techniques discussed will be illustrated by many real examples involving biological and social science data. Examples and exercises will be implemented in a statistical software package "Stata", but familiarity with Stata is not required.

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STATISTICS 23400. Statistical Models and Methods.
Sec 01: Linda Collins, MWF, 11:30-12:20 PM, Eckhart 133.
Sec 02: David Degras, TTh, 3:00-4:20 PM, Eckhart 133.
PQ: Mathematics 13300, 15300 or 16300, or equivalent.
Required Reading: Statistics for the Sciences by Buntinas and Funk 2005, Duxbury (Thomson Brooks/Cole). ISBN-10: 0534387748 ISBN-13: 978-0534387747.

Students who matriculate in the College after September 2008 may count either STAT 22000 or STAT 23400, but not both, toward the forty-two credits required for graduation.

This course presents basic ideas of probability theory and statistics, and is recommended for students throughout the natural and social sciences who want a broad background in statistical methodology and exposure to probability models and the statistical concepts underlying the methodology. Probability is developed for the purpose of modeling outcomes of random phenomena. Random variables and their expectations are studied; including means and variances of linear combinations, and an introduction to conditional expectation. Binomial, hypergeometric, Poisson, exponential, normal and other standard probability distributions are considered. Some probability models are studied mathematically and others via simulation on a computer. Sampling distributions and related statistical methods are explored mathematically, studied via simulation and illustrated on data. Statistical methods for describing data and making inferences based on samples from populations are presented. Methods include, but are not limited to, inference for proportions and means for one- and two-sample problems, correlation and simple linear regression. Graphical and numerical data description are used for exploration, communication of results, and comparing mathematical consequences of probability models and data. Mathematics is employed to the level of univariate calculus and is less demanding than that required by STAT 24400.

Univariate calculus and computer simulation are used throughout the course to investigate statistical concepts and their mathematical underpinnings. One full year of univariate calculus is a prerequisite for the course (Math 13300, 15300, or 16300). Students with AP Calculus credit for any of these prerequisite courses may also enroll. Familiarity with at least limits, derivatives and integrals of polynomial and exponential functions, change of variable (substitution) in definite integrals, max-min problems, use of summation notation, and sequences and series as well as a willingness to explore ideas mathematically are key to your success in this course. See http://statistics.uchicago.edu/~stat234 for more detailed information.

Stat 23400 takes the mathematical prerequisite quite seriously. Enrolling concurrently in either Math 13300, 15300, or 16300 while taking Stat 23400 is very strongly discouraged. Further, students who do not feel strong mathematically, may want to wait until completing their entire mathematical requirement (e.g., Math 19520-19620 for Economics majors) before enrolling in Stat 23400. Economics majors are strongly encouraged to delay taking Stat 23400 until the quarter just before enrolling in their required econometrics course (Econ 21000), for which Stat 23400 is a prerequisite. Thus, delaying Stat 23400 until at least late in the second year or even early in the third year of the Economics degree program should not be considered unusual.

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STATISTICS 24400. Statistical Theory/Method-1
Sec 01: Mathias Drton, TuTh, 1:30-2:50 PM, Eckhart 133
Sec 02: Michael Stein, MW, 1:30-2:50 PM, Stuart 101
PQ:  Multivariate Calculus (Math 19520 or 20000 or equivalent and Linear Algebra (Math 19620), 25500 or Stat 24300 or equivalent).
Required Reading: Rice, John A. (2007). Mathematical Statistics and Data Analysis, Third Edition, by (Duxbury).

This is the first quarter of a two-quarter sequence. Enrollment in the first quarter alone is permitted, although not recommended. The first quarter will cover the essential tools from probability needed for study of statistical theory and the basic elements of statistical theory.

Topics will include the definitions of probability and random variables, binomial and other discrete probability distributions, normal and other continuous probability distribution, joint probability distributions and the transformation of random variables, principles of inference (including Bayesian inference), maximum likelihood estimation, hypothesis testing and confidence intervals, likelihood ratio tests, multinomial distributions and chi-square tests. Some large sample theory will be included. The emphasis will be upon statistical theory, specifically upon concepts and tools that are useful for understanding and applying statistical methodology.

There is no enforced prerequisite in probability or statistics, although the pace is such that students may find it useful to have taken a previous elementary course. The coverage of topics in probability will be limited, so that those who have taken a course in probability will find reinforcement rather than redundancy. The second quarter will cover statistical methodology, including some multivariate analysis, the analysis of variance, the regression phenomenon, linear regression analysis, data analysis, and correlation.

The mathematics prerequisites are listed as general guidance. You should be comfortable with multivariate calculus through partial differentiation and multiple integration. Linear algebra is generally used only in 24500 and not 24400.

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Graduate Courses

STATISTICS 30400.  Distribution Theory
Sec 01: Dan Nicolae, MWF, 1:30-2:20 PM, Eckhart 117
PQ: STAT 24500 or MATH 25000 or equivalent
Recommended reading: Severini, T. (2005). Elements of Distribution Theory. Cambridge University Press.

This course covers the basics of distribution theory. Topics include:

  • Distribution functions and their inverses, quantile functions, Q/Q plots, change-of-variables for probability densities
  • Expectation, variance, median, mode of random variables
    Basics of measure theory, including Fubini's theorem and interchangeability of limits and integrals
  • Moment generating functions and characteristic functions, including power series expansion, inversion formulas, uniqueness theorems, and convergence in distribution
  • Cumulants and cumulant generating functions: examples, properties
  • Different concepts of convergence for random variables
  • Limit theorems, including the weak law of large numbers, the central limit theorem.

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STATISTICS 30700=CMSC 37800.  Numerical Computation
Sec 01: Ronald Thisted, TTh, 9:00-10:20 AM, Eckhart 117
PQ: Linear Algebra (Stat 34300 or equivalent) and some previous experience with Statistics.
Required reading: Thisted, Ronald A. Elements of Statistical Computation. CRC/Chapman & Hall.
Recommended, but not required:  

  • Gentle, James. Random Number Generation and Monte Carlo Methods. Second edition.    Springer.
  • Watkins, David S. Fundamentals of Matrix Computations. Second edition.    Wiley.
  • Scheinerman, Edward. C++ for Mathematicians. CRC/Chapman and Hall.

This course starts with a presentation of the fundamental algorithms for the solution of linear equations, the decomposition of matrices, and finite dimensional eigenvalue problems. Applications to least squares/regression will be presented, emphasizing use of existing numerical software. The course will also discuss optimization problems and introduce the basic principles of simulation-based methods.

Topics include:

  • Gaussian elimination and back-substitution
  • LU decomposition. (General/Symmetric)
  • Singular value decomposition. (Symmetric)
  • Householder orthogonalization and QR factorization. (Symmetric).
  • Iterative methods: Jacobi and Gauss Seidel.
  • Optimization: Newton-Raphson and quasi-Newton.
  • Uniform random number generation.
  • Simulating specific distributions
  • Monte Carlo methods

By the end of the course students should be able to apply these algorithms in their research work.

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STATISTICS 32300=HSTD 43000. Bayesian Methods and Computation.
Sec 01:  Vanja Dukic, TTh, 3:00-4:20 PM, Eckhart 117.
PQ:  STAT 301-302; 343; 312-313; OR consent of instructor.
Required reading: Tanner, 3rd ed., Tools for Statistical Inference: Methods for the Exploration of Posterior Distributions and Likelihood Functions, Springer.

This course will cover basics of modern statistical computation, with emphasis on Bayesian computational methods. It will begin with the introduction to Bayesian statistics, and cover normal and non-normal approximation to likelihood and posterior distributions, the EM algorithm, data augmentation and Markov Chain Monte Carlo (MCMC) methods. Time permitting, we will conclude with some recent developments in the MCMC area, such as perfect and adaptive sampling methods. Biostatistical and environmental examples will be given throughout the course. There will be weekly homeworks, and students will be expected to complete a project by the end of the course. There will be no final exam, but there will be an in-class final project presentation. Algorithms can be implemented in any language, but familiarity with R and Matlab will be assumed.

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STATISTICS 33500=GSBC 41910. Time-Series Analysis/Forecast
Sec 01:  Ruey-Shiong Tsay, Thu, 8:30-11:30 AM, GSB HC3B
PQ:  Business 41901 or consent of instructor.
Required reading: No textbook. Some selected reference books are given below:

  • Time Series Analysis, J. Hamilton, Princeton University Press, 1994.
  • Analysis of Financial Time Series , 2nd Edition, Ruey S. Tsay, Wiley, 2005.
  • A Course in Time Series Analysis, ed. Pena, Tiao and Tsay, Wiley, 2001.

GSB Honor Code: This course requires students to follow the GSB Honor Code and Standards of Scholarship in examinations and homework assignments. The GSB Honor Code requires students to sign the following pledge, "I pledge my honor that I have not violated the Honor Code during this examination," on every examination.

Course Ob jective:

  • To introduce time series analysis for econometric and financial applications
  • To discuss time series forecasting
  • To gain experience in model building
  • To assess the impacts of interventions and outliers
  • To understand state-space models and Kalman filter
  • To study MCMC methods and their applications in time series analysis
  • To discuss unit-root theory, trend-stationarity, testing and applications.

Lecture: Thursdays 8:30 to 11:30 am, starting September 25
Lecture Notes:
Outline of the lecture and some supplementary material will be posted on the web:
http://faculty.chicagogsb.edu/ruey.tsay/teaching/uts/.

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STATISTICS 33610. Asymptotics for Time Series.
Sec 01:  Wei Biao Wu, MW, 1:30-2:50 PM, Eckhart 117.
PQ:  Business 30200 and STAT 31300 or consent of instructorf instructor.
Required reading:
Fan, J. and Yao, Q., (2003). Nonlinear time series, nonparametric and parametric methods. Springer, New York.
Wu, W. B. (2005): Nonlinear system theory: Another look at dependence. Proceedings of the National Academy of Sciences USA. 102, 14150--14154.
Wu, W. B. and Zhibiao Zhao (2007) Inference of Trends in Time Series. Journal of the Royal Statistical Society, Series B, 69, 391--410

I will present a systematic asymptotic theory for time series analysis. In particular, I will discuss asymptotics for sample mean, sample variances, banded covariance matrices estimates, inference of trends, periodograms, spectral density estimates, quantile estimation, nonparametric estimates, VaR and long-range dependent processes. Some asymptotic theory for non-stationary processes and functional linear models will also be presented.

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STATISTICS 34300.  Applied Linear Stat Methods
Sec 01: Mathias Drton, TTh, 9:00-10:20 AM, Eckhart 133
PQ: STAT 24500 or equivalent and Linear Algebra (Stat 24300 or equivalent).
Optional Reading: Venables, W.N. and Ripley, B.D. (1999). Modern Applied Statistics with S-Plus (3rd ed). Springer-Verlag.
Required Reading: Weisberg, S. (2005). Applied Linear Regression, Third Edition. John Wiley & Sons. Software: Splus or R.

Statistics 34300 is an intensive course in the theory and methods of linear regression and related techniques of statistical modelling. It is intended primarily for graduate students in Statistics and related fields.

The course is also open to undergraduates and others who have a solid understanding of matrix algebra and basic statistical theory. Thorough familiarity with the simple linear regression model is expected.

The course will review linear regression with a single predictor, and will cover the multiple-predictor case; least-squares estimation; associated distribution theory; estimation, confidence intervals and tests; regression with errors in the predictors; weighted least squares, assessing lack of fit; residual analysis; regression diagnostics; transformations; model building; collinearity; subset-selection methods, including stepwise regression; prediction; nonlinear least squares.

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STATISTICS 35000=HSTD 30900, ENST 27400, PPHA 36400.  Principles of Epidemiology.
Sec 01: Kurina Lianne , MW, 10:30-11:50 AM, BSLC arr.
PQ: Introductory Statistics
Required reading:
Gordis, Leon. Epidemiology, 4th Ed. 2008. Saunders (available at the Barnes and Noble campus bookstore or at Amazon.com)
Original epidemiological articles (available on course website)

Epidemiology is the study of the distribution and determinants of health and disease in human populations. This course introduces the basic principles of epidemiologic study design, analysis and interpretation through lectures, assignments, and critical appraisal of both classic and contemporary research articles.

OBJECTIVES

  • To be able to critically read and understand epidemiologic studies.
  • To be able to calculate and interpret measures of disease occurrence and measures of disease-exposure associations.
  • To understand the contributions of epidemiology to clinical research, medicine, and public health.

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STATISTICS 35201=HSTD 32901. Intro to Clinical Trials.
Sec 01: James Dignam, Tu, 3:00-5:50 PM, BH W230. Other ‘field trips’ as discussed below, will be recommended as additions or substitutes for class meetings.
PQ: Introductory statistics course (HSTD 32100, STAT 22000, or similar), ability to use a personal computer, or, permission of instructor.
Required reading: Piantadosi, S. Clinical Trials: A Methodologic Perspective, 2nd Edition 2005, Wiley Interscience, New York.
Reference: Friedman, L.M., Furberg, C.D., DeMets, D.L. Fundamentals of Clinical Trials., 3rd ed., 1998, Springer, New York.
Cook, T.D., DeMets, D.L. Introduction to Statistical Methods for Clinical Trials, 2007, Chapman & Hall/CRC, London.
Other readings: Selected articles for class discussion will be identified and distributed the prior week. A reading list of these methodological articles, commentaries, and clinical trial report articles will be developed and distributed.

This course will review major components of clinical trial conduct, including the formulation of clinical hypotheses and study endpoints, trial design, development of the research protocol, trial progress monitoring, analysis, and the summary and reporting of results. Other aspects of clinical trials to be discussed include ethical and regulatory issues in human sub jects research, data quality control, meta-analytic overviews and consensus in treatment strategy resulting from clinical trials, and the broader impact of clinical trials on public health.

The course will be conducted partly via lectures and partly in a ‘reading’ format. Designated individuals may take the lead in covering a main topic, with participation and input by all. Similarly, presentation of materials in the special topics portion of the class meeting will be shared among all.

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STATISTICS 36900=HSTD 33300.  Longitudinal Data Analysis.
Sec 01:  Paul Rathouz, TTh, 9:00-10:20 AM, BSLC 313.
PQ: Statistics 220 (introductory statistical methods), Health Studies 321 or equivalent, Health Studies 324 / Statistics 224 (Applied Regression Analysis) or equivalent, and Health Studies 327 / Statistics 227 (Biostatistical Methods) or equivalent; or permission of instructor. Facility with the Stata software package is assumed.
Required reading: (Available in bookstore.)
* Fitzmaurice GM, Laird NM, Ware JH. (2004). Applied Longitudinal Analysis. Hoboken, NJ: Wiley-Interscience.
Other references: (* Indicates text on reserve in Eckhart Library.)
* Diggle PJ, Heagerty P, Liang K-Y, & Zeger SL. (2002). Analysis of Longitudinal Data, 2nd edn. Oxford: Oxford University Press.
* Hedeker DR & Gibbons RD. (2006). Longitudinal data analysis. Hoboken, NJ: Wiley-Interscience. Hand D, Crowder M. (1996). Practical Longitudinal Data Analysis. London: Chapman & Hall.
Lindsey JK. (1999). Models for repeated measurements. New York: Oxford University Press.
Littel RC, Milliken GA, Stroup WA, Wolfinger RD. (1996). SAS System for Mixed Models. Cary, NC: SAS Institute.
* McCulloch CE, Searle SR. (2001). Generalized, Linear, and Mixed Models. New York: John Wiley & Sons.
Verbeke G, Molenberghs G. (2000). Linear mixed models for longitudinal data. New York: Springer.

Longitudinal data consist of multiple measures over time on a sample of individuals. This type of data occurs extensively in both observational and experimental biomedical and public health studies, as well as in studies in sociology and applied economics. This course will provide an introduction to the principles and methods for the analysis of longitudinal data. Emphasis will be on data analysis and interpretation. Supporting statistical theory will be given at a level appropriate for an advanced Master’s student in Statistics. Problems will be motivated by applications in epidemiology, clinical medicine, health services research, and disease natural history studies.

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STATISTICS 38100.  Measure-Theoretic Probability I.
Sec 01: Michael Wichura, MWF, 2:30-3:20 PM, Eckhart 117.
PQ: STAT 31300 or consent of instructor.
Required Reading: There is no text required or recommended. Notes will be provided.

This course is the first of a three quarter sequence presenting a careful development of some topics from measure and probability. Topics to be covered in 381 include: classes of sets -- fields, sigmafields, monotone classes, pi and lambda systems; probabilities and general measures; independence and the Borel-Cantelli lemmas; measurable functions; induced measures, distribution and inverse distribution functions; integration with respect to measures -- basic properties, change of variable, indefinite integration, densities; integration to the limit -- MCT, DCT, and friends; laws of large numbers, applications to probability and statistics; transition probabilities and product measures.

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STATISTICS 39000=FINM 34500. Stochastic Calculus I.
Sec 01: Per Mykland, M, 6:30-9:30 PM, Ryerson 251.
PQ: Enrollment in Mathematical Finance M. Sc. program or consent of instructor.
Required Reading:  Stochastic Calculus for Finance I-II, by Steven E. Shreve (required).
A Course in Financial Calculus, by Alison Etheridge (highly recommended).
`The basics of S-PLUS'', 3rd edition, by the same authors (A. Krause and M. Olson), ISBN 0-387-95456-2 (required).

This course is an introduction to stochastic calculus as it is relevant to the pricing and hedging of options and other derivative securities. It is the first of a two-quarter sequence offered in collaboration by the Department of Statistics and the master's program in Mathematical Finance. The main topics to be covered are:

  • The Fundamental Theorem of Asset Pricing
  • Martingales
  • Brownian Motion
  • The Ito Integral and Ito's Formula
  • The Black-Sholes Formula
  • Girsanov's Formula
  • Currency Options
  • The Martingale Representation and Hedging

There will be weekly homework assignments, and midterm and final exams. The course assistants will conduct weekly help sessions on Friday afternoons.

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STATISTICS 47620. Simulation Methods.
Sec 01: Steven P. Lalley, MWF, 10:30-11:20 AM, Eckhart 117
PQ: STAT 24600 or STAT 31200 or consent of instructor. Stat 47620 will be taught starting October 27th, 2008 and credits will be 50.
Required Reading: Monte Carlo Strategies in Scientific Computing by Jun Liu.

This will be a brief introduction to several useful techniques of simulation:

  • importance sampling
  • MCMC (Markov chain Monte Carlo)
  • Gibbs sampling
  • perfect sampling

The utility of these methods will be illustrated by a number of substantial examples, including

  • enumeration of contingency tables with fixed margins
  • simulation of Ising models
  • code-breaking.