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Dan Nicolae
Dan Nicolae
Professor, Departments of Statistics; Human Genetics; Medicine; Section of Genetic Medicine; the College
Senior Fellow: Computation Institute

Web: http://www.stat.uchicago.edu/~nicolae/
E-mail: nicolae@galton.uchicago.edu
Phone: 773.702.4837
Fax: 773-702-9810

University of Chicago
Department of Statistics
5734 S. University Avenue
Eckhart 127
Chicago, IL 60637


Research Interests

My major research interests are in the areas of statistical genetics and mathematical statistics. The problems I am studying are mainly motivated by applications to studies on the genetics of common/complex diseases.

Statistical genetics problems of interest include likelihood applications to complex trait gene detection, genome-wide strategies for testing gene-gene and gene-environment interaction, association with copy-number variation, methods for analysing data from genome-wide association studies at the gene/pathway/network level, and measures of relative information in genetic studies.

The applications I work on focus on finding the genetic and environmental components of asthma, inflammatory bowel disease, and diabetic complications. I am also interested in functional genomics and the analysis of gene expression data.

Mathematical statistics topics I am working on include Bayesian and frequentist ways of measuring the amount of missing data, general measures of information, and artificial likelihoods for hypothesis testing.

Last update: 8/29/12